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Two NFC East heavyweights will clash when the Dallas Cowboys host the Philadelphia Eagles on Saturday. Both teams are postseason-bound, and the Eagles can lock up the division with a win. However, MVP candidate Jalen Hurts could miss the game with a shoulder injury. The Cowboys are reeling after an overtime upset defeat at the hands of the Jaguars and will be eager to get back on track. The Eagles, meanwhile, have won five in a row and will get tight end Dallas Goedert back from injured reserve. The Cowboys are six-point favorites in the latest Week 15 NFL odds at Caesars Sportsbook. Which Week 16 NFL lines should you target with your Week 16 NFL bets? Before you make any Week 16 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 15 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season. The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is WAY UP. Now, the model has locked in five confident NFL best bets for Week 16. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 16 NFL picks at SportsLine.
Top Week 16 NFL picksAfter simulating every game 10,000 times, the model is high on the Minnesota Vikings (-3.5) to cover against the New York Giants. The Vikings put together the biggest comeback win in NFL history last Saturday, erasing a 33-0 deficit to win 39-36 in overtime. Kirk Cousins threw for an absurd 417 yards in the second half and overtime, displaying that Vikings can be a truly dangerous team on offense.Impact players like wide receiver Justin Jefferson can shred opposing defenses. That is one reason the Vikings are covering the spread in over 50% of simulations. See which other NFL parlay picks to make here.How to make Week 16 NFL parlaysThe model also jumped on four other NFL matchups where it says the line is way off, including a pair of underdogs that have a chance to win outright. You can only see the model’s NFL Week 16 best bets and parlay at SportsLine.
What are the model’s top Week 16 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 16 NFL best bets from a model on a 157-113 run on its top-rated picks, and find out.